Ran Elkon Mayezana

Redifferentiation of expanded human islet β cells by

Ex-vivo expansion of adult human islet β cells has been evaluated for generation of abundant insulin-producing cells for transplantation; however, lineage-tracing has demonstrated that this process results in β-cell dedifferentiation.

Beatrice Milon's research works

Beatrice Milon's 20 research works with 105 citations and 844 reads, including: Biological insights from multi-omic analysis of 31 genomic risk loci for adult hearing difficulty

Dissection of a DNA-damage-induced

Apr 13, 2005 · The four major expression patterns in the damage-induced gene set revealed by cluster analysis. For each of the 112 damage-induced genes, the fold change in expression level 4 h after NCS treatment was computed in uninfected cells and in the cells knocked-down for Rel-A, p53 and ATM, yielding a 112 × 4 data matrix, with the rows corresponding to genes.

BMC Genomics BioMed Central

BioMed Central Page 1 of 16 (page number not for citation purposes) BMC Genomics Research article Open Access Functional genomic delineation of TLR-induced transcriptional networks Ran Elkon†1, Chaim Linhart†2, Yonit Halperin2, Yosef Shiloh1 and Ron Shamir*2

Activity-dependent neuroprotective protein (ADNP) is an

Jun 27, 2018 · Neuroadaptations in the brain reward system caused by excessive alcohol intake, lead to drinking escalation and alcohol use disorder phenotypes. Activity-dependent neuroprotective protein (ADNP ...

Elkton Police Department, Cecil, MD

2018-11-06 13:44:03. The Elkton Police Department is happy to announce that our very own CPL Todd Finch was recognized this past Friday Night at the Cecil County First Responders Appreciation Dinner sponsored by the Cecil County Chamber of Commerce.

Transcription factor and microRNA - PubMed Central (PMC)

We thank Gidi Weber and Adi Maron-Katz for their contributions to the source code. Promoter sequences were downloaded by Ran Elkon. We also thank the anonymous referees for their constructive comments. R.S. was supported in part by the Raymond and Beverly Sackler Chair in Bioinformatics and by a grant from the Wolfson Foundation.

Systematic identification of functional SNPs interrupting 3’ UTR

25-09-2019 · Alternative polyadenylation (APA) is emerging as a widespread regulatory layer as the majority of human protein-coding genes contain several polyadenylation (p(A)) sites in their 3’ UTRs. By generating isoforms with different 3’ UTR length, APA potentially affects mRNA stability, translation efficiency, nuclear export, and cellular localization. Polyadenylation sites are regulated by adjacent …

Amkush Pal Ambush Pal | Amlatwi

Browse by Name. Browse for your friends alphabetically by name. Numbers 0 to 25 contain non-Latin character names. Note: This only includes people who have Public Search Listings available on Facebook.

MBA in Healthcare Innovation

Dr. Ran Elkon . The main goal of the course is to provide students with intuitive yet deep understanding of basic concepts in statistical data analysis and inference.

In the news! | Sackler Faculty of Medicine

Nov 25, 2019 · Ran Elkon and his team at Tel Aviv University find widespread technical bias in RNA-Seq datasets. Their research was recently published in The Scientist.

Exxon Valdez

At the time of the spill, Exxon Valdez was employed to transport crude oil from the Alyeska consortium's pipeline terminal in Valdez, Alaska, to the lower 48 states of the United States. At the time it ran aground, the vessel was carrying about 201,000 m³ (53.1 million gallons) of oil.

Eastern Auditory Retreat

2017 Eastern Auditory Retreat (EAR) Meeting at Georgetown University. ... Alisha Beirl, Yoko Ogawa, Yang Song, Ran Elkon, Beatrice Milon, Katie Kindt, ...

Sackler Faculty of Medicine Preclinical Research 2019

Sackler Faculty of Medicine Research 4 The Sackler Faculty of Medicine Table of Contents Cancer and Molecular Therapies 8 Dr. Yaron Carmi, Ph.D. 9 Prof. Neta Erez, Ph.D. 11

Staff Directory

Tel Aviv University, P.O. Box 39040, Tel Aviv 6997801, Israel. UI/UX Basch_Interactive Basch_Interactive

Recurrent functional misinterpretation of RNA-seq data caused by

Analysis of numerous RNA-seq datasets reveals a recurrent sample-specific length bias that causes frequent false positive calls by gene-set enrichment analyses, leading to functional misinterpretation of the data. Its removal requires methods that allow the integration of gene length as sample-specific covariate.

Open Access E2F mediates enhanced alternative polyadenylation

BibTeX @MISC{Elkon_openaccess, author = {Ran Elkon and Jarno Drost and Gijs Van Haaften and Mathias Jenal and Mariette Schrier and Joachim Af and Oude Vrielink and Reuven Agami}, title = {Open Access E2F mediates enhanced alternative polyadenylation in proliferation}, year = {}}

The EXPANDER Integrated Platform for Transcriptome Analysis

Introduction. The ability to profile entire cellular transcriptomes, first by expression microarrays and subsequently by RNA-sequencing (RNA-seq) has transformed biological research over the last two decades, by turning the paradigm of systems-level analysis from a formidable task to one that is readily accessible to most experimental laboratories .Consequently, transcriptome profiling is one of the most …

News Page (Biology & Evolution)

Dec 18, 2019 · The study was conducted by Dr. Shir Mandelbaum, Dr. Zohar Manber, Dr. Orna Elroy-Stein and Dr. Ran Elkon at TAU's Sackler Faculty of Medicine and George S. Wise Faculty of Life Sciences and was published on November 12 in PLOS Biology.

CT-FOCS: a novel method for inferring cell type-specific

Jul 18, 2019 · Spatiotemporal gene expression patterns are governed to a large extent by enhancer elements, typically located distally from their target genes. Identification of enhancer-promoter (EP) links that are specific and functional in individual cell types is a key challenge in understanding gene regulation. We introduce CT-FOCS, a new statistical inference method that utilizes multiple replicates ...

Faculty Healthcare Innovation

Dr. Ran Elkon PhD in Bioinformatics, Tel Aviv University. Dr. Elkon is the principal investigator at the bioinformatics research lab for gene regulation at the Sackler School of Medicine, Tel Aviv University.

Elkon, Ran - Netherlands Cancer Institute

Ran Elkon Experience My bioinformatics research is focused on different post-transcriptional layers of gene regulation, including microRNAs, RNA-binding proteins, alternative polyadenylation (APA) and protein translation, and understanding how mis-regulation of these layers is associated with human disease, especially cancer.

Discovery of 4-{4-[(3R)-3-Methylmorpholin-4-yl]-6-[1

Michal Gavish-Izakson, Bhagya Bhavana Velpula, Ran Elkon, Rosario Prados-Carvajal, Georgina D Barnabas, Alejandro Pineiro Ugalde, Reuven Agami, Tamar Geiger, Pablo Huertas, Yael Ziv, Yosef Shiloh. Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair.

SPIKE

SPIKE is a database of highly curated human signaling pathways with an associated interactive software tool. Users can view and download individual pathway maps and browse the entire database from this website, or launch a map viewer tool that allows dynamic visualization of the database and save networks in XGMML format that can be viewed in all generic XGMML viewers.

November 2019: Elkon: Technical bias in RNA sequencing

A new study by Dr. Ran Elkon, Edmond J. Safra faculty fellow (Medicine) and colleagues, identifies a frequent technical bias in RNA-seq data.. Reproducibility is a major challenge in experimental biology, and with the increasing complexity of data generated by genomic-scale techniques this concern is immensely amplified.

CiteSeerX — Removal of AU Bias from Microarray mRNA

BibTeX @MISC{Elkon08removalof, author = {Ran Elkon and Reuven Agami}, title = {Removal of AU Bias from Microarray mRNA Expression Data Enhances Computational Identification of Active}, year = {2008}}

‫مهرجان " رب الكون ميزنا بميزه " حمو بيكا - علي قدوره - نور

Oct 02, 2018 · FigoEld5lawe مهرجان " رب الكون ميزنا بميزه " حمو بيكا - علي قدوره - نور التوت - توزيع فيجو الدخلاوي 2019

CiteSeerX — Genome-wide In-silico Identification of

BibTeX @MISC{Elkon_genome-widein-silico, author = {Ran Elkon and Chaim Linhart and Roded Sharan and Ron Shamir and Yosef Shiloh}, title = {Genome-wide In-silico Identification of Transcriptional Regulators Controlling Cell Cycle in Human Cells}, year = {}}

FOCS: a novel method for analyzing enhancer and gene activity

May 01, 2018 · Background. Deciphering the regulatory role of the noncoding part of the human genome is a major challenge. With the completion of the sequencing of the genome, efforts have shifted over the past decade towards understanding the epigenome.

Ran Elkon Mayezana

What Does The Name Mayezana. Fun Facts about the name Mayezana. How unique is the name Out of 5,933,561 records in the U.S. Social Security Administration public data, the first name Mayezana …

Characterization of noncoding regulatory DNA in the human

Genome-wide mapping of regulatory elements will improve our understanding of how genetic variation in the noncoding genome affects disease phenotypes. Genetic variants associated with common ...

Roded Sharan Homepage

EXPANDER - an integrative program suite for microarray data analysis (with Ron Shamir, Adi Maron-Katz, Amos Tanay, Chaim Linhart, Israel Steinfeld, Yosef Shiloh and Ran Elkon) Journal: BMC Bioinformatics 6, p. 232, 2005: pdf. Islands of Tractability for Parsimony Haplotyping (with Bjarni Halldorsson and Sorin Istrail)

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